Research finds stress accelerates immune aging

Washington: Published in the research of the ‘Proceedings of the National Academy of Sciences’ (PNAS) on June 13, a study explains age-related health inequalities, including the unequal toll of the pandemic on people, and identifies potential intervention points.

“As the world’s population of older adults increases, understanding disparities in age-related health is essential. Age-related changes in the immune system play a critical role in declining health,” said lead study author Eric Klopack, a postdoctoral scholar in the USC Leonard Davis School of Gerontology. “This study helps clarify mechanisms involved in accelerated immune aging.” As people age, the immune system naturally begins a dramatic downgrade, a condition called immunosenescence. With advanced age, a person’s immune profile weakens, and includes too many worn-out white blood cells circulating and too few fresh, “naive” white blood cells ready to take on new invaders.

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